Description
Mounjaro (tirzepatide) is an injectable medication that’s used with diet and exercise to treat type 2 diabetes in adults.
The use of Mounjaro has not been studied in patients who have had pancreatitis.
Mounjaro should not be used in patients with type 1 diabetes.
Fact Table |
|
Formula |
C225H348N48O68 |
License |
US FDA |
Bioavailability |
80% |
Legal status |
Rx-Only |
Chemical Name |
Tirzepatide |
Elimination half-life |
Five days |
Dosage (Strength) |
– |
Pregnancy |
Insufficient data |
Brands |
Mounjaro |
Protein binding |
Albumin |
PubChem CID |
156588324 |
MedlinePlus |
a622044 |
ChEBI |
– |
ATC code |
– |
DrugBank |
DB15171 |
KEGG |
D11360 |
Routes of administration |
Subcutaneous |
Directions
Mounjaro is available in 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg per 0.5 mL single-dose injectable pens.
Follow the instructions that come with your Mounjaro prescription. Talk to your doctor or pharmacist about your questions or concerns.
Use Mounjaro as instructed by your doctor.
Mounjaro should be injected subcutaneously in the abdomen, thigh, or upper arm. Injection sites should be rotated with each dose.
Mounjaro dosage:
The recommended starting dose is to inject 2.5 mg subcutaneously once a week with or without food and increased to 5 mg subcutaneously once a week after 4 weeks of treatment. The dosage may be increased by 2.5 mg increments at 4-week intervals depending on medication response. The dose should not exceed 15 mg subcutaneously once a week.
Ingredients
Mounjaro contains tirzepatide, a glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist.
Contraindications
Do not use Mounjaro if you or your family has a history of a type of thyroid cancer known as medullary thyroid carcinoma or if you have Multiple Endocrine Neoplasia syndrome type 2.
Do not use Mounjaro if you are allergic to tirzepatide or any of the other ingredients or excipients contained in Mounjaro.
Cautions
WARNING: RISK OF THYROID C-CELL TUMORS
|
WARNING: RISK OF THYROID C-CELL TUMORS
See full prescribing information for complete boxed warning.
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- Discuss your medications, allergies, medical problems, and pregnancy or breastfeeding status with your doctor before you begin treatment with Mounjaro.
- Mounjaro may cause pancreatitis.
- Mounjaro may cause low blood sugar if used with insulin or another type of medication that can lower blood sugar. Test your blood sugar levels and treat low blood sugar as your doctor has instructed.
- Mounjaro may cause allergic reactions that can be severe. Get emergency care right away if you develop shortness of breath, swelling of your face, lips, tongue, or throat, rash, or rapid heart rate.
- Mounjaro can cause acute kidney damage.
- Mounjaro can cause gastrointestinal events that can be severe.
- Mounjaro can cause acute gallbladder disease.
- Patients who have had diabetic retinopathy should be monitored for complications or worsening of diabetic retinopathy.
Side Effects
The most common side effects experienced with Mounjaro include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach pain.
Call your doctor right away if you have side effects that bother you or won’t go away.
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